Publications

Journals

J.A. Champion and S. Mitragotri. “Role of target geometry in phagocytosis.” PNAS. 103(13), 4930-4934. 2006. (PNAS cover image by JAC, commentary J. Cell Biol. 173(1), 2006.)

J.A. Champion, Y.K. Katare and S. Mitragotri. “Particle shape: A new design parameter for micro and nanoscale drug delivery carriers.” J. Control. Release. 121(1), 3-9. 2007.

J.A. Champion, Y.K. Katare and S. Mitragotri. “Making polymeric micro- and nanoparticles of complex shapes.” PNAS. 104(29), 11901-11904. 2007. (commentary Science 317(5838), 2007 and C&E News 85(29), 2007.)

J.A. Champion, A. Walker and S. Mitragotri. “Role of particle size in phagocytosis of polymeric microspheres.” Pharm. Res. 25(8), 1815-1821. 2008.

S. Muro, C. Garnacho, J.A. Champion, J. Leferovich, C. Gajewski, E. Schuchman, S. Mitragotri and V.R. Muzykantov. “Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.” Mol. Ther. 16(8), 1450-1458. 2008.

J.A. Champion and S. Mitragotri. “Shape induced inhibition of phagocytosis of polymer particles.” Pharm. Res. 26(1), 244-249. 2009.

J.T. Ngo, J.A. Champion, A. Mahdavi, I.C. Tanrikulu, K.E. Beatty, R.E. Connor,      T.H. Yoo, D.C. Dieterich, E.M. Shuman and D.A. Tirrell. “Cell-selective metabolic labeling of proteins.” Nat. Chem. Biol. 5(10), 715-717. 2009. (Nat. Chem. Biol. cover image by JAC, commentary Nature 460(805), 2009.)

 

Chapters

J.A. Champion and S. Mitragotri. “Ch 15: UFOs, worms, and surfboards: What shapes teach us about cell-material interactions.” Advances in Regenerative Medicine: Role of Nanotechnology and Engineering Principles. V.P. Shastri et al. (eds). Springer. 2010.

 

Patent Applications

J.A. Champion, Y.K. Katare and S. Mitragotri. “Engineering shape of polymeric micro- and nanoparticles.” Filed 2007.

J.A. Champion and S. Mitragotri. “Coated hyaluronic acid particles.” Filed 2008.

J.A. Champion, S. Mitragotri and Ahmet Tezel. “Swellable hyaluronic acid particles.” Filed 2010.