For the most updated list of publications from this group, please visit this site.


J.A. Champion and S. Mitragotri. “Ch 15: UFOs, worms, and surfboards: What shapes teach us about cell-material interactions.” Advances in Regenerative Medicine: Role of Nanotechnology and Engineering Principles. V.P. Shastri et al. (eds). Springer. 2010.

Patent Applications

J.A. Champion, Y.K. Katare and S. Mitragotri. “Engineering shape of polymeric micro- and nanoparticles.” Filed 2007.

J.A. Champion and S. Mitragotri. “Coated hyaluronic acid particles.” Filed 2008.

J.A. Champion, S. Mitragotri and Ahmet Tezel. “Swellable hyaluronic acid particles.” Filed 2010.


Garapaty A, Champion JA. "Tunable particles alter macrophage uptake based on combinatorial effects of physical properties." Bioengineering & Translational Medicine. (2016)

Park W, Yee CM, Champion JA. "Self-assembled hybrid supraparticles that proteolytically degrade tumor necrosis factor-α." Journal of Materials Chemistry B. (2016) 4(9):1633-9.

Padmore T, Stark C, Turkevich LA, Champion JA. "Quantitative analysis of the role of fiber length on phagocytosis and inflammatory response by alveolar macrophages." Biochimica et biophysica acta. (2016). PubMed PMID:27784615

Jang Y, Champion JA. "Self-Assembled Materials Made from Functional Recombinant Proteins." Accounts of chemical research. (2016); 49(10): 2188-2198. PubMed PMID: 27677734

Park WM, Champion JA. "Colloidal Assembly of Hierarchically Structured Porous Supraparticles from Flower-Shaped Protein-Inorganic Hybrid Nanoparticles." ACS nano. (2016); 10(9):8271-80. PubMed PMID:  27552189

Wang L, Chang TZ, He Y, Kim JR, Wang S, Mohan T, Berman Z, Tompkins SM, Tripp RA, Compans RW, Champion JA, Wang BZ. "Coated protein nanoclusters from influenza H7N9 HA are highly immunogenic and induce robust protective immunity." Nanomedicine : nanotechnology, biology, and medicine. (2016). PubMed PMID: 27622321

Herrera Estrada LP, Padmore TJ, Champion JA. "Bacterial Effector Nanoparticles as Breast Cancer Therapeutics." Mol. Pharmaceutics. (2016) DOI: 10.1021/acs.molpharmaceut.5b0037

Park WM, Yee CM, Champion JA. Self-assembled hybrid supraparticles that proteolytically degrade tumor necrosis factor-α. J Mater Chem B. 2016. DOI:10.1039/C5TB01647A

Garapaty A, Champion JA. Non-covalent phosphorylcholine coating reduces protein adsorption and phagocytic uptake of microparticles. Chem Commun. 2015. DOI:10.1039/C5CC03459K.

Garapaty, A. and J. A. Champion (2015). "Biomimetic and synthetic interfaces to tune immune responses." Biointerphases 10(3): 030801.

Zan X, Garapaty A, Champion JA. Engineering Polyelectrolyte Capsules with Independently Controlled Size and Shape. Langmuir. 2015.

Herrera Estrada LP, Champion JA. Protein nanoparticles for therapeutic protein delivery. Biomaterials Science. 2015;3(6):787-799.

Tiernan, A. R., J. A. Champion, et al. (2015). "Trichostatin A affects the secretion pathways of beta and intestinal endocrine cells." Experimental Cell Research 330(1): 212-221.

Park, W. M. and J. A. Champion (2014). "Thermally Triggered Self-Assembly of Folded Proteins into Vesicles." Journal of the American Chemical Society.

Silverman, B. R. and J. A. Champion (2014). "Presentation of fibronectin fragments using affinity protein interactions for enhanced retention and function." Acta Biomaterialia 10(12): 4956-4960

Estrada, L. H., S. Chu, et al. (2014). "Protein Nanoparticles for Intracellular Delivery of Therapeutic Enzymes." Journal of Pharmaceutical Sciences 103(6): 1863-1871

Wang L, Hess A, Chang TZ, Wang YC, Champion JA, Compans RW, Wang BZ. "Nanoclusters self-assembled from conformation-stabilized influenza M2e as broadly cross-protective influenza vaccines." Nanomedicine: Nanotechnology, Biology and Medicine 10(2): 473-482

W.M. Park and J.A. Champion. “Two-Step Protein Self-Assembly in the Extracellular Matrix.” Angew. Chem. Int. Ed. (2013) 52.31, 8098-8101.

J.T. Ngo, B.M. Babin, J.A. Champion, E.M. Shuman and D.A. Tirrell. “State-selective metabolic labeling of cellular proteins.” ACS Chem. Biol .(2012) 7.8, 1326-1330. (commentary C&E News online, 2012.)

J.A. Champion and S. Mitragotri. “Role of target geometry in phagocytosis.” PNAS. 103(13), 4930-4934. 2006. (PNAS cover image by JAC, commentary J. Cell Biol. 173(1), 2006.)

J.A. Champion, Y.K. Katare and S. Mitragotri. “Particle shape: A new design parameter for micro and nanoscale drug delivery carriers.” J. Control. Release. 121(1), 3-9. 2007.

J.A. Champion, Y.K. Katare and S. Mitragotri. “Making polymeric micro- and nanoparticles of complex shapes.” PNAS. 104(29), 11901-11904. 2007. (commentary Science 317(5838), 2007 and C&E News 85(29), 2007.)

J.A. Champion, A. Walker and S. Mitragotri. “Role of particle size in phagocytosis of polymeric microspheres.” Pharm. Res. 25(8), 1815-1821. 2008.

S. Muro, C. Garnacho, J.A. Champion, J. Leferovich, C. Gajewski, E. Schuchman, S. Mitragotri and V.R. Muzykantov. “Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.” Mol. Ther. 16(8), 1450-1458. 2008.

J.A. Champion and S. Mitragotri. “Shape induced inhibition of phagocytosis of polymer particles.” Pharm. Res. 26(1), 244-249. 2009.

J.T. Ngo, J.A. Champion, A. Mahdavi, I.C. Tanrikulu, K.E. Beatty, R.E. Connor,      T.H. Yoo, D.C. Dieterich, E.M. Shuman and D.A. Tirrell. “Cell-selective metabolic labeling of proteins.” Nat. Chem. Biol. 5(10), 715-717. 2009. (Nat. Chem. Biol. cover image by JAC, commentary Nature 460(805), 2009.)